Publication
RNA thermometer controls temperature-dependent virulence factor expression in Vibrio cholerae
Weber GG, Kortmann J, Narberhaus F, Klose KE
Proceedings of the National Academy of Sciences of the United States of America · 2014
RNA regulationVibrio choleraeBacterial virulence
Why this matters, in plain language
Cholera bacteria move from cool water into a 37°C gut. This work found that a folded piece of RNA keeps a virulence gene unreadable until it warms — a thermometer built from the message itself, needing no sensor protein at all.
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Cite this
Weber GG, Kortmann J, Narberhaus F, Klose KE. RNA thermometer controls temperature-dependent virulence factor expression in Vibrio cholerae. Proc Natl Acad Sci U S A. 2014;111(39):14241-6. doi:10.1073/pnas.1411570111